Acute hypercapnia and gas exchange in ARDS.
نویسندگان
چکیده
1 Ahuja A, Gothi D, Joshi J. A 52-year-old man with daytime sleepiness, sialorrhea, and facial fasciculations. Chest 2006; 130:287–290 2 Servera E, Sancho J. Appropriate management of respiratory problems is of utmost importance in the treatment of patients with amyotrophic lateral sclerosis [editorial]. Chest 2005; 127:1879–1882 3 Aboussouan LS, Khan SU, Meeker DP, et al. Effect of noninvasive positive-pressure ventilation on survival in amyotrophic lateral sclerosis. Ann Intern Med 1997; 127:450–453 4 Bach JR. Amyotrophic lateral sclerosis: prolongation of life by noninvasive respiratory aids. Chest 2002; 122:92–98 5 Lechtzin N, Shade D, Clawson L, et al. Supramaximal inflation improves lung compliance in subjects with amyotrophic lateral sclerosis. Chest 2006; 129:1322–1329 6 Farrero E, Prats E, Povedano M, et al. Survival in amyotrophic lateral sclerosis with home mechanical ventilation. Chest 2005; 127:2132–2138 7 Simonds AK. Ethics and decision making in end stage lung disease. Thorax 2003; 58:272–277
منابع مشابه
Gas Exchange Disturbances Regulate Alveolar Fluid Clearance during Acute Lung Injury
Disruption of the alveolar-capillary barrier and accumulation of pulmonary edema, if not resolved, result in poor alveolar gas exchange leading to hypoxia and hypercapnia, which are hallmarks of acute lung injury and the acute respiratory distress syndrome (ARDS). Alveolar fluid clearance (AFC) is a major function of the alveolar epithelium and is mediated by the concerted action of apically-lo...
متن کاملInfluenza A H1N1 induces declines in alveolar gas exchange in mice consistent with rapid post‐infection progression from acute lung injury to ARDS
BACKGROUND Patients with severe seasonal or pandemic influenza pneumonia frequently develop acute respiratory distress syndrome (ARDS). One clinical diagnostic criterion for ARDS is the P(a)O(2):F(i)O(2) ratio, which is an index of alveolar gas exchange. However, effects of H1N1 influenza infection on P(a)O(2):F(i)O(2) ratios and related pathophysiologic readouts of lung function have not been ...
متن کاملAirway pressure release ventilation and prone positioning in severe acute respiratory distress syndrome.
BACKGROUND Implementation of lung protective strategy in the treatment of severe Acute Respiratory Distress Syndrome (ARDS) has been reported to be associated with improved outcome. To fulfil this approach, sedation, neuromuscular blocking agents and full mechanical ventilatory support are often used in critical failure of gas exchange. CASE REPORT We present a patient who developed multiple ...
متن کاملThe lung and carbon dioxide: implications for permissive and therapeutic hypercapnia.
Although acute respiratory acidosis may be a sign of impending respiratory failure in spontaneously breathing patients, it is commonly encountered in intubated patients with acute lung injury (ALI). This is especially the case now that limiting tidal volumes and airway pressures have been proven to reduce mortality in ALI, presumably by reducing additional lung injury caused by mechanical venti...
متن کاملCARDIOVASCULAR RESPONSES TO HYPERCAPNIA AND VARYING LEVELS OF ARTERIAL pH IN THE ANESTHETIZED CAT
Effects of acute hypercapnia on the cardiovascular system (CYS) were studied in the anesthetized cat. After surgery the animal was exposed to a gas mixture of 12% CO2 and 25% O2 in nitrogen, and hypercapnia with low levels of arterial pH (pHa) was produced for 20 minutes. In the second run the same level of hypercapnia was induced by ventilating the same cat from the above gas mixture but ...
متن کاملQuantitative evaluation of hemodynamic parameters during acute alveolar hypoxia and hypercapnia in the isolated ventilated-perfused rabbit lung
Introduction: Acute respiratory disorders such as obstructive pulmonary diseases and hypoventilation may lead to alveolar hypoxia and hypercapnia which their effects on pulmonary vascular beds are controversial. The aim of this study was to establish the isolated perfused lung setup and investigate the effects of alveolar hypoxia and hypercapnia on pulmonary vascular resistance. Methods: White ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Chest
دوره 130 6 شماره
صفحات -
تاریخ انتشار 2006